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Dipòsit Digital de Documents de la UAB 3 registres trobats  La cerca s'ha fet en 0.01 segons. 
1.
12 p, 1.1 MB Dysfunctional telomeres in primary cells from Fanconi anemia FANCD2 patients / Joksic, Ivana (University of Belgrade. Vinca Institute of Nuclear Sciences (Belgrad, Sèrbia)) ; Vujic, Dragana (University of Belgrade. School of Medicine (Belgrad, Sèrbia)) ; Guc-Scekic, Marija (Mother and Child Health Care Institute of Serbia "Dr Vukan Cupic" (Belgrad, Sèrbia)) ; Leskovac, Andreja (University of Belgrade. Vinca Institute of Nuclear Sciences (Belgrad, Sèrbia)) ; Petrovic, Sandra (University of Belgrade. Vinca Institute of Nuclear Sciences (Belgrad, Sèrbia)) ; Ojani, Maryam (Brunel University (Londres, Regne Unit)) ; Trujillo Quintero, Juan Pablo (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Surrallés i Calonge, Jordi (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Zivkovic, Maja (University of Belgrade. Vinca Institute of Nuclear Sciences (Belgrad, Sèrbia)) ; Stankovic, Aleksandra (University of Belgrade. Vinca Institute of Nuclear Sciences (Belgrad, Sèrbia)) ; Slijepcevic, Pedrag (Brunel University (Londres, Regne Unit)) ; Joksic, Gordana (University of Belgrade. Vinca Institute of Nuclear Sciences (Belgrad, Sèrbia))
Background: Fanconi anemia (FA) is characterized by sensitivity to DNA cross-linking agents, mild cellular, and marked clinical radio sensitivity. In this study we investigated telomeric abnormalities of non-immortalized primary cells (lymphocytes and fibroblasts) derived from FA patients of the FA-D2 complementation group, which provides a more accurate physiological assessment than is possible with transformed cells or animal models. [...]
2012 - 10.1186/2041-9414-3-6
Genome integrity, Vol. 3, N. 6 (September 2012) , p. 1-12  
Registre complet - Creative Commons
2.
10 p, 2.1 MB Gene amplification in human cells knocked down for RAD54 / Ruiz-Herrera Moreno, Aurora (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Smirnova, Alexandra (Università di Pavia. Dipartimento di Genetica e Microbiologia "Adriano Buzzati-Traverso") ; Khouriauli, Lela (Università di Pavia. Dipartimento di Genetica e Microbiologia "Adriano Buzzati-Traverso") ; Nergadze, Solomon G. (Università di Pavia. Dipartimento di Genetica e Microbiologia "Adriano Buzzati-Traverso") ; Mondello, Chiara (Istituto di Genetica Molecolare (Pàvia, Itàlia)) ; Giulotto, Elena (Università di Pavia. Dipartimento di Genetica e Microbiologia "Adriano Buzzati-Traverso") ; Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí"
Background: In mammalian cells gene amplification is a common manifestation of genome instability promoted by DNA double-strand breaks (DSBs). The repair of DSBs mainly occurs through two mechanisms: non-homologous end-joining (NHEJ) and homologous recombination (HR). [...]
2011 - 10.1186/2041-9414-2-5
Genome integrity, Vol. 2, N. 5 (March 2011) , p. 1-10
2 documents
Registre complet - Creative Commons
3.
10 p, 531.4 KB Fanconi anemia protein FANCD2 inhibits TRF1 polyADP-ribosylation through tankyrase1-dependent manner / Lyakhovich, Alex (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Ramírez de Haro, Ma. José (Duke-NUS Graduate Medical School. Cancer and Stem Cell Research Program) ; Castellanos, Andres (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Castellà, Maria (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Simons, A. M. (Harvard Medical School. Department of Pathology) ; Parvin, J. D. (Harvard Medical School. Department of Pathology) ; Surrallés i Calonge, Jordi (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Background: Fanconi anemia (FA) is a rare autosomal recessive syndrome characterized by developmental abnormalities, progressive bone marrow failure, and predisposition to cancer. The key FA protein FANCD2 crosstalks with members of DNA damage and repair pathways that also play a role at telomeres. [...]
2011 - 10.1186/2041-9414-2-4
Genome integrity, Vol. 2, N. 4 (February 2011) , p. 1-10  
Registre complet - Creative Commons

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